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Article

White matter abnormalities in major depression: evidence from post-mortem, neuroimaging and genetic studies.

Journal of affective disorders - 1 Jul 2011

Tham Ming Wei, Woon Puay San, Sum Min Yi, Lee Tih-Shih, Sim Kang

Abstract excerpt

BACKGROUND: Until more recently, most studies have examined the changes in brain gray matter in major depressive disorder (MDD) with less studies focusing on understanding white matter pathology in MDD. Studies of brain white matter volume changes, connectivity disruptions, as well as genetic factors affecting myelination can throw light on the nature of white matter abnormalities underpinning MDD. METHODS: We...

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Identifiers

PMID: 20889213
DOI: 10.1016/j.jad.2010.09.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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