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Article

Coding region polymorphisms in the indoleamine 2,3-dioxygenase (INDO) gene and recurrent spontaneous abortion.

Journal of reproductive immunology - 1 Jan 2011

Amani Dawar, Ravangard Fatemeh, Niikawa Norrio, Yoshiura Ko-Ichiro, Karimzadeh Mojtaba, Dehaghani Alamtaj Samsami, Ghaderi Abbas

Abstract excerpt

Indoleamine 2,3-dioxygenase (INDO) catalyzes degradation of the indole ring of indoleamines and locally depletes tryptophan. INDO expression suppresses T cell proliferation and activation. Genetic variation in the INDO gene may contribute to the variable INDO enzyme expression, activity and severity of some diseases. Recurrent spontaneous abortion (RSA) is a common pregnancy complication and the exact causes of...

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PMID: 21030093
DOI: 10.1016/j.jri.2010.07.007

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CGA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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