Article
Prion genotypes of scrapie-infected Canadian sheep 1998-2008.
Canadian journal of veterinary research = Revue canadienne de recherche veterinaire - 1 Jul 2010
Harrington Noel P, O'Rourke Katherine I, Feng Yuqin, Rendulich Jasmine, Difruscio Cathleen, Balachandran Aru
Abstract excerpt
This report describes the genetics of the prion protein gene (PRNP) at codons 136, 154, and 171 for sheep diagnosed with naturally acquired classical scrapie in Canada between 1998 and 2008. Genotyping analysis was performed on 249 sheep with confirmed classical scrapie infection representing 98 flocks from 6 provinces. A further case-control analysis of 3 of these flocks compared the genotypes between infected...
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