Article
Risk of scrapie in British sheep of different prion protein genotype.
The Journal of general virology - 1 Sept 2004
Baylis M, Chihota C, Stevenson E, Goldmann W, Smith A, Sivam K, Tongue S, Gravenor M B
Abstract excerpt
There is a well-established association between sheep prion protein (PrP) genotype and the risk of death from scrapie. Certain genotypes are clearly associated with susceptibility to the disease and others to resistance. However, there have been no attempts to quantify the disease risk for all 15 PrP genotypes. Here, datasets of the PrP genotypes of nearly 14 000 British sheep and of more than 1500 confirmed...
Topics
- Age Factors
- Alleles
- Animals
- Genetic Predisposition to Disease
- Genotype
- Prions
- Risk Factors
- Scrapie
- Sheep
- United Kingdom