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Article

Cellular abundance of Mps1 and the role of its carboxyl terminal tail in substrate recruitment.

The Journal of biological chemistry - 3 Dec 2010

Sun Tingting, Yang Xiaomei, Wang Wei, Zhang Xiaojuan, Xu Quanbin, Zhu Songcheng, Kuchta Robert, Chen Guanjun, Liu Xuedong

Abstract excerpt

Mps1 is a protein kinase that regulates normal mitotic progression and the spindle checkpoint in response to spindle damage. The levels of Mps1 are relatively low in cells during interphase but elevated in mitosis or upon activation of the spindle checkpoint, although the dynamic range of Mps1 ex...

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Identifiers

PMID: 20884615
DOI: 10.1074/jbc.M110.177642
PMCID: PMC2992306

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20884615-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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