Article
Drosophila variable nurse cells encodes arrest defective 1 (ARD1), the catalytic subunit of the major N-terminal acetyltransferase complex.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Nov 2010
Wang Ying, Mijares Michelle, Gall Megan D, Turan Tolga, Javier Anna, Bornemann Douglas J, Manage Kevin, Warrior Rahul
Abstract excerpt
Mutations in the Drosophila variable nurse cells (vnc) gene result in female sterility and oogenesis defects, including egg chambers with too many or too few nurse cells. We show that vnc corresponds to Arrest Defective1 (Ard1) and encodes the catalytic subunit of NatA, the major N-terminal acetyl-transferase complex. While N-terminal acetylation is one of the most prevalent covalent protein modifications in...
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