<i>TMPRSS2–ERG</i> gene fusion prevalence and class are significantly different in prostate cancer of caucasian, african‐american and japanese patients

Abstract excerpt

BACKGROUND: Prostate cancer (PCa) exhibits significant differences in prevalence and mortality among different ethnic groups. The underlying genetics is not well understood. TMPRSS2-ERG fusion is a common recurrent chromosomal aberration in PCa and is however not studied among different ethnic groups. We examined the prevalence and class of TMPRSS2-ERG gene fusion in PCa from Caucasian, African-American, and...

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