Article
mutL as a genetic switch of bacterial mutability: turned on or off through repeat copy number changes.
FEMS microbiology letters - 1 Nov 2010
Chen Fang, Liu Wei-Qiao, Liu Zhen-Hong, Zou Qing-Hua, Wang Ye, Li Yong-Guo, Zhou Jin, Eisenstark Abraham, Johnston Randal N, Liu Gui-Rong, Yang Bao-Feng, Liu Shu-Lin
Abstract excerpt
Bacterial adaptation to changing environments can be achieved through the acquisition of genetic novelty by accumulation of mutations and recombination of laterally transferred genes into the genome, but the mismatch repair (MMR) system strongly inhibits both these types of genetic changes. As mu...
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