Article
Amplification of mutator cells in a population as a result of horizontal transfer.
Journal of bacteriology - 1 Jun 2001
Funchain P, Yeung A, Stewart J, Clendenin W M, Miller J H
Abstract excerpt
Mutator cells that lack the mismatch repair system (MMR(-)) occur at rates of 10(-5) or less in laboratory populations started from wild-type cells. We show that after selection for recombinants in an interspecies mating between Salmonella enterica serovar Typhimurium and Escherichia coli, the percentage of MMR(-) cells rises to several percent of the recombinant population, and after a second successive mating...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
