Article
Spontaneous conversion between mutL and 6 bpDeltamutL in Salmonella typhimurium LT7: association with genome diversification and possible roles in bacterial adaptation.
Genomics - 1 Oct 2007
Gong Jun, Liu Wei-Qiao, Liu Gui-Rong, Chen Fang, Li Jun-Qian, Xu Guo-Min, Wang Ling, Johnston Randal N, Eisenstark Abraham, Liu Shu-Lin
Abstract excerpt
Previously, we reported the phenomenon of genome diversification in Salmonella typhimurium LT7, i.e., individual strains derived from LT7 kept changing the genome structure by inversions, translocations, duplications, and mutations. To elucidate the genetic basis, we sequenced selected genes of the mismatch repair (MMR) system for correlations between MMR defects and genome diversification. We chose S....
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