Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multiple genetic switches spontaneously modulating bacterial mutability.

BMC evolutionary biology - 13 Sept 2010

Chen Fang, Liu Wei-Qiao, Eisenstark Abraham, Johnston Randal N, Liu Gui-Rong, Liu Shu-Lin

Abstract excerpt

BACKGROUND: All life forms need both high genetic stability to survive as species and a degree of mutability to evolve for adaptation, but little is known about how the organisms balance the two seemingly conflicting aspects of life: genetic stability and mutability. The DNA mismatch repair (MMR) system is essential for maintaining genetic stability and defects in MMR lead to high mutability. Evolution is driven...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Bacteria
Share to Bacterial Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Biological Evolution

Share to DNA Mismatch Repair

Share to Mutation

Share to Tandem Repeat Sequences

Source

Open in PubMed Open full text

Identifiers

PMID: 20836863
DOI: 10.1186/1471-2148-10-277
PMCID: PMC2955026

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multiple genetic switches spontaneously modulating bacterial mutability.PMID 20836863Read ↗

Spontaneous modulation of a dynamic balance between bacterial genomic stability and mutability: roles and molecular mechanisms of the genetic switch.Semantic proximity Read ↗

mutL as a genetic switch of bacterial mutability: turned on or off through repeat copy number changes.Semantic proximity Read ↗

The microbiology of mutability.Semantic proximity Read ↗

Mutators Enhance Adaptive Micro-Evolution in Pathogenic MicrobesSemantic proximity Read ↗

The role of mutators in the emergence of antibiotic-resistant bacteria.Semantic proximity Read ↗

Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing.Semantic proximity Read ↗

Distribution of mutation frequencies among Salmonella enterica isolates from animal and human sources and genetic characterization of a Salmonella Heidelberg hypermutator.Semantic proximity Read ↗

SPONTANEOUS MUTATORS IN BACTERIA: Insights into Pathways of Mutagenesis and RepairSemantic proximity Read ↗

Nutrient-dependent growth defects and mutability of mutators in Escherichia coli.Semantic proximity Read ↗

The balance between mutators and nonmutators in asexual populations.Semantic proximity Read ↗

Competition between transposable elements and mutator genes in bacteria.Semantic proximity Read ↗

Impact of transient acquired hypermutability on the inter- and intra-species competitiveness of Pseudomonas aeruginosa.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.