Article
Failure to confirm CNVs as of aetiological significance in twin pairs discordant for schizophrenia.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Oct 2010
Ono Shinji, Imamura Akira, Tasaki Shinya, Kurotaki Naohiro, Ozawa Hiroki, Yoshiura Koh-ichiro, Okazaki Yuji
Abstract excerpt
Copy number variations (CNVs) are common structural variations in the human genome that strongly affect genomic diversity and can play a role in the development of several diseases, including neurodevelopmental disorders. Recent reports indicate that monozygotic twins can show differential CNV profiles. We searched CNVs in monozygotic twins discordant for schizophrenia to identify susceptible loci for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
