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Article

Copy number variation analysis of twin pairs discordant for cleft lip with or without cleft palate.

International journal of immunopathology and pharmacology - 1 Jan 2000

Scapoli Luca, Carinci Francesco, Palmieri Annalisa, Cura Francesca, Baj Alessandro, Beltramini Giada, Docimo Raffaella, Martinelli Marcella

Abstract excerpt

Non-syndromic cleft lip with or without cleft palate (nsCL/P) is a frequent orofacial malformation. The comparison of concordance rate observed in monozygotic and dizygotic twins supports high level of heritability and a strong genetic component. However, phenotype concordance for orofacial cleft in monozygotic twins is about 50%. The aim of the present investigation was to detect postzygotic events that may...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31663445
DOI: 10.1177/2058738419855873
PMCID: PMC6822181

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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