Article

Copy Number Variation Analysis of 100 Twin Pairs Enriched for Neurodevelopmental Disorders

2017-06-20

Abstract excerpt

Hundreds of penetrant risk loci have been identified across different neurodevelopmental disorders (NDDs), and these often involve rare (<1% frequency) copy number variations (CNVs), which can involve one or more genes. Monozygotic (MZ) twin pairs are long thought to share 100% of their genomic information. However, genetic differences in the form of postzygotic somatic variants have been reported recently both in...

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Literature Corpus work: 936491f8-4d78-56be-a6f5-6d8ce5d5acb1
DOI: 10.1101/152611

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