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Article

Loci polymorphisms of the APOBEC3G gene in HIV type 1-infected Brazilians.

AIDS research and human retroviruses - 1 Feb 2011

Bizinoto Maria Clara, Leal Elcio, Diaz Ricardo Sobhie, Janini Luiz Mário

Abstract excerpt

The human APOBEC3G (A3G) protein activity obstructs retrovirus infection by inducing mutations of guanosines to adenosines (G → A) in the viral DNA. These G → A mutations may disrupt the reading frames of the viral genes. It has been observed that A3G polymorphisms can affect the degree of G → A mutations and the disease progression. For example, one study showed that the nonsynonymous substitution H186R was...

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PMID: 20874421
DOI: 10.1089/aid.2010.0146

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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