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Article

APOBEC3G genetic variants and their influence on the progression to AIDS.

Journal of virology - 1 Oct 2004

An Ping, Bleiber Gabriela, Duggal Priya, Nelson George, May Margaret, Mangeat Bastien, Alobwede Irene, Trono Didier, Vlahov David, Donfield Sharyne, Goedert James J, Phair John, Buchbinder Susan, O'Brien Stephen J, Telenti Amalio, Winkler Cheryl A

Abstract excerpt

The cytosine deaminase APOBEC3G, in the absence of the human immunodeficiency virus type 1 (HIV-1) accessory gene HIV-1 viral infectivity factor (vif), inhibits viral replication by introducing G-->A hypermutation in the newly synthesized HIV-1 DNA negative strand. We tested the hypothesis that genetic variants of APOBEC3G may modify HIV-1 transmission and disease progression. Single nucleotide polymorphisms were...

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Identifiers

PMID: 15452227
DOI: 10.1128/JVI.78.20.11070-11076.2004
PMCID: PMC521814

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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