Article
Association of single nucleotide polymorphisms of APOBEC3G with susceptibility to HIV-1 infection and disease progression among men engaging in homosexual activity in northern China.
Archives of virology - 1 Jan 2017
Li Qiuyan, Qiao Yuandong, Zhang Guangfa, He Ning, Zhang Xuelong, Jia Xueyuan, Sun Haiming, Wang Chuntao, Xu Lidan
Abstract excerpt
Men who have sex with men (MSM) are at high risk of HIV infection. The APOBEC3G (apolipoprotein B mRNA editing catalytic polypeptide 3G) protein is a component of innate antiviral immunity that inhibits HIV-1 replication. In the present study, a total of 483 HIV-1 seropositive men and 493 HIV-1 seronegative men were selected to investigate the association between single nucleotide polymorphisms (SNPs) of the...
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