Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nucleophosmin mutations in Chinese adults with acute myelogenous leukemia.

Annals of hematology - 1 Feb 2009

Ruan Guo-Rui, Li Jin-Lan, Qin Ya-Zhen, Li Ling-Di, Xie Min, Chang Yan, Zhang Yan, Liu Yan-Rong, Jiang Bin, Chen Shan-Shan, Huang Xiao-Jun

Abstract excerpt

Recently, mutations in the nucleophosmin (NPM1) gene were detected in 50-60% of adult acute myelogenous leukemia (AML) patients, mainly with a normal karyotype. In this study, we detected typical NPM1 mutations (types A, B, D) in untreated Chinese AML patients using real-time quantitative polymerase chain reaction (RQ-PCR) followed by sequence analysis. The detection rate of NPM1 mutations in 220 AML patients was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to China
Share to Follow-Up Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Dosage

Share to Leukemia, Myeloid, Acute

Share to Nuclear Proteins

Share to Nucleophosmin

Share to Plasmids

Share to Sensitivity and Specificity

Source

Identifiers

PMID: 18726096
DOI: 10.1007/s00277-008-0591-8

Genes

NPM1
FLT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Nucleophosmin mutations in Chinese adults with acute myelogenous leukemia.PMID 18726096Read ↗

Analysis of NPM1 gene mutations in Chinese adults with acute myeloid leukemia.Semantic proximity Read ↗

Quantitative detection of circulating nucleophosmin mutations DNA in the plasma of patients with acute myeloid leukemia.Semantic proximity Read ↗

FMS-Like Tyrosine Kinase 3 (FLT3) and Nucleophosmin 1 (NPM1) in Iranian Adult Acute Myeloid Leukemia Patients with Normal Karyotypes: Mutation Status and Clinical and Laboratory Characteristics.Semantic proximity Read ↗

Nucleophosmin mutations in de novo acute myeloid leukemia: the age-dependent incidences and the stability during disease evolution.Semantic proximity Read ↗

FLT3 and NPM1 mutations in Chinese patients with acute myeloid leukemia and normal cytogenetics.Semantic proximity Read ↗

Chronic myelomonocytic leukemia with nucleophosmin (NPM1) mutation.Semantic proximity Read ↗

Detection of nucleophosmin and FMS-like tyrosine kinase-3 gene mutations in acute myeloid leukemia.Semantic proximity Read ↗

Clinical prognostic value of different NPM1 mutations in acute myeloid leukemia patients.Semantic proximity Read ↗

Nucleophosmin gene mutations in acute myeloid leukemia.Semantic proximity Read ↗

Characteristics and clinical behavior of acute myeloid leukemia harboring rare non-A/B/D nucleophosmin (NPM1) gene mutation subtypes: a single-center experience and review of the literature.Semantic proximity Read ↗

Nucleophosmin mutation in de-novo acute myeloid leukemia.Semantic proximity Read ↗

Clonal heterogeneity in patients with cytogenetically normal acute myeloid leukemia with NPM1 mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.