Article
FLT3 and NPM1 gene mutations in childhood acute myeloblastic leukemia.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Mukda Ekchol, Pintaraks Katsarin, Sawangpanich Rachchadol, Wiangnon Surapon, Pakakasama Samart
Abstract excerpt
Mutations of receptor tyrosine kinases are implicated in the constitutive activation and development of human hematologic malignancies. Mutations in fms-like tyrosine kinase 3 (FLT3) gene including internal tandem duplication (ITD) and point mutation in the tyrosine kinase domain (TKD) as well as...
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