Article
Identification of a cell death pathway in Candida albicans during the response to pheromone.
Eukaryotic cell - 1 Nov 2010
Alby Kevin, Schaefer Dana, Sherwood Racquel Kim, Jones Stephen K, Bennett Richard J
Abstract excerpt
Mating in hemiascomycete yeasts involves the secretion of pheromones that induce sexual differentiation in cells of the opposite mating type. Studies in Saccharomyces cerevisiae have revealed that a subpopulation of cells experiences cell death during exposure to pheromone. In this work, we tested whether the phenomenon of pheromone-induced death (PID) also occurs in the opportunistic pathogen Candida albicans....
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