Many of the genes required for mating in <i>Saccharomyces cerevisiae</i> are also required for mating in <i>Candida albicans</i>

Abstract excerpt

Candida albicans is the single, most frequently isolated human fungal pathogen. As with most fungal pathogens, the factors which contribute to pathogenesis in C. albicans are not known, despite more than a decade of molecular genetic analysis. Candida albicans was thought to be asexual until the discovery of the MTL loci homologous to the mating type (MAT) loci in Saccharomyces cerevisiae led to the demonstration...

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