Article
Intracellular generation of superoxide by the phagocyte NADPH oxidase: how, where, and what for?
Free radical biology & medicine - 15 Dec 2010
Bylund Johan, Brown Kelly L, Movitz Charlotta, Dahlgren Claes, Karlsson Anna
Abstract excerpt
Professional phagocytes increase their consumption of molecular oxygen during the phagocytosis of microbes or when encountering a variety of nonparticulate stimuli. In these circumstances, oxygen is reduced by the phagocyte NADPH oxidase, and reactive oxygen species (ROS), which are important for the microbicidal activity of the cells, are generated. The structure and function of the NADPH oxidase have been...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
