Article
NADPH oxidase.
The international journal of biochemistry & cell biology - 1 Nov 1996
Shatwell K P, Segal A W
Abstract excerpt
Superoxide is instrumental in the killing of microorganisms by phagocytic cells. It is generated by the NADPH oxidase system, a membrane-bound electron transport complex which pumps electrons from NADPH in the cytoplasm across the wall of the phagocytic vacuole to molecular oxygen. Superoxide deficiency results in the genetically inherited condition Chronic Granulomatous Disease (CGD), in which the patient is...
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