Article
A mutation in the receptor binding site enhances infectivity of 2009 H1N1 influenza hemagglutinin pseudotypes without changing antigenicity.
Virology - 25 Nov 2010
Wang Wei, Castelán-Vega Juan A, Jiménez-Alberto Alicia, Vassell Russell, Ye Zhiping, Weiss Carol D
Abstract excerpt
The 2009 H1N1 pandemic highlights the need to better understand influenza A infectivity and antigenicity. Relative to other recent seasonal H1N1 influenza strains, the 2009 H1N1 virus grew less efficiently in eggs, which hindered efforts to rapidly supply vaccine. Using lentiviral pseudotypes bea...
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