Article
Degradation, Recycling, and Shedding of <i>Trypanosoma brucei</i> Variant Surface Glycoprotein
1 Nov 1990
Abstract excerpt
Trypanosoma brucei bloodstream forms express a densely packed surface coat consisting of identical variant surface glycoprotein (VSG) molecules. This surface coat is subject to antigenic variation by sequential expression of different VSG genes and thus enables the cells to escape the mammalian host's specific immune response. VSG turnover was investigated and compared with the antigen switching rate. Living...
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