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How Does the VSG Coat of Bloodstream Form African Trypanosomes Interact with External Proteins?

31 Dec 2015

Abstract excerpt

Variations on the statement "the variant surface glycoprotein (VSG) coat that covers the external face of the mammalian bloodstream form of Trypanosoma brucei acts a physical barrier" appear regularly in research articles and reviews. The concept of the impenetrable VSG coat is an attractive one, as it provides a clear model for understanding how a trypanosome population persists; each successive VSG protects the...

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PMID: 26719972
DOI: 10.1371/journal.ppat.1005259

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