Article
Genetic susceptibility to type 2 diabetes and breast cancer risk in women of European and African ancestry.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2012
Hou Ningqi, Zheng Yonglan, Gamazon Eric R, Ogundiran Temidayo O, Adebamowo Clement, Nathanson Katherine L, Domchek Susan M, Rebbeck Timothy R, Simon Michael S, John Esther M, Hennis Anselm, Nemesure Barbara, Wu Suh-Yuh, Leske M Cristina, Ambs Stefan, Niu Qun, Zhang Jing, Pierce Brandon, Cox Nancy J, Olopade Olufunmilayo I, Huo Dezheng
Abstract excerpt
BACKGROUND: Epidemiologic studies have reported a positive association between type 2 diabetes (T2D) and breast cancer risk, independent of body weight. METHODS: We investigated 40 genetic variants known to be associated with T2D in relation to breast cancer risk among 2,651 breast cancer cases and 2,520 controls of African or European ancestry that were pooled from seven studies. RESULTS: We found that two T2D...
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