Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.

PLoS genetics - 1 Apr 2011

Sim Xueling, Ong Rick Twee-Hee, Suo Chen, Tay Wan-Ting, Liu Jianjun, Ng Daniel Peng-Keat, Boehnke Michael, Chia Kee-Seng, Wong Tien-Yin, Seielstad Mark, Teo Yik-Ying, Tai E-Shyong

Abstract excerpt

Recent large genome-wide association studies (GWAS) have identified multiple loci which harbor genetic variants associated with type 2 diabetes mellitus (T2D), many of which encode proteins not previously suspected to be involved in the pathogenesis of T2D. Most GWAS for T2D have focused on populations of European descent, and GWAS conducted in other populations with different ancestry offer a unique opportunity...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asia, Southeastern
Share to Cyclin-Dependent Kinase 5

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Type 2

Share to Genetic Loci

Share to Genome-Wide Association Study

Share to Kinesins

Share to Linkage Disequilibrium

Share to tRNA Methyltransferases

Source

Open in PubMed Open full text

Identifiers

PMID: 21490949
DOI: 10.1371/journal.pgen.1001363
PMCID: PMC3072366

Genes

CDKAL1
HHEX
IDE
KIF11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia.PMID 21490949Read ↗

Progress in Defining the Genetic Contribution to Type 2 Diabetes in Individuals of East Asian Ancestry.Semantic proximity Read ↗

Trans-ethnic fine mapping identifies a novel independent locus at the 3' end of CDKAL1 and novel variants of several susceptibility loci for type 2 diabetes in a Han Chinese population.Semantic proximity Read ↗

Identification of type 2 diabetes loci in 433,540 East Asian individualsSemantic proximity Read ↗

Transferability and fine mapping of type 2 diabetes loci in African Americans: the Candidate Gene Association Resource Plus Study.Semantic proximity Read ↗

Susceptibility Loci for Type 2 Diabetes in the Ethnically Endogamous Indian Sindhi Population: A Pooled Blood Genome-Wide Association Study.Semantic proximity Read ↗

Identification of type 2 diabetes loci in 433,540 East Asian individuals.Semantic proximity Read ↗

Replication of type 2 diabetes candidate genes variations in three geographically unrelated Indian population groups.Semantic proximity Read ↗

Cross-sectional and longitudinal replication analyses of genome-wide association loci of type 2 diabetes in Han Chinese.Semantic proximity Read ↗

Replication and Relevance of Multiple Susceptibility Loci Discovered from Genome Wide Association Studies for Type 2 Diabetes in an Indian Population.Semantic proximity Read ↗

Validation of type 2 diabetes risk variants identified by genome-wide association studies in Han Chinese population: a replication study and meta-analysis.Semantic proximity Read ↗

Transancestral fine-mapping of four type 2 diabetes susceptibility loci highlights potential causal regulatory mechanisms.Semantic proximity Read ↗

Genome-wide association study and trans-ethnic meta-analysis identify novel susceptibility loci for type 2 diabetes mellitus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.