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Article

C. elegans SWAN-1 Binds to EGL-9 and regulates HIF-1-mediated resistance to the bacterial pathogen Pseudomonas aeruginosa PAO1.

PLoS pathogens - 26 Aug 2010

Shao Zhiyong, Zhang Yi, Ye Qi, Saldanha Jenifer Neeta, Powell-Coffman Jo Anne

Abstract excerpt

Pseudomonas aeruginosa is a nearly ubiquitous human pathogen, and infections can be lethal to patients with impaired respiratory and immune systems. Prior studies have established that strong loss-of-function mutations in the egl-9 gene protect the nematode C. elegans from P. aeruginosa PAO1 fast...

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Identifiers

PMID: 20865124
DOI: 10.1371/journal.ppat.1001075
PMCID: PMC2928816

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20865124-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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