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Article

An essential role for XBP-1 in host protection against immune activation in C. elegans.

Nature - 25 Feb 2010

Richardson Claire E, Kooistra Tristan, Kim Dennis H

Abstract excerpt

The detection and compensatory response to the accumulation of unfolded proteins in the endoplasmic reticulum (ER), termed the unfolded protein response (UPR), represents a conserved cellular homeostatic mechanism with important roles in normal development and in the pathogenesis of disease. The...

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Share to Caenorhabditis elegans Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20182512
DOI: 10.1038/nature08762
PMCID: PMC2834299

Genes

XBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20182512-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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An essential role for XBP-1 in host protection against immune activation in C. elegans.PMID 20182512Read ↗

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