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Article

A HIF-independent mediator of transcriptional responses to oxygen deprivation in Caenorhabditis elegans.

Genetics - 1 Mar 2015

Padmanabha Divya, Padilla Pamela A, You Young-Jai, Baker Keith D

Abstract excerpt

The adaptive response to hypoxia is accompanied by widespread transcriptional changes that allow for prolonged survival in low oxygen. Many of these changes are directly regulated by the conserved hypoxia-inducible factor-1 (HIF-1) complex; however, even in its absence, many oxygen-sensitive transcripts in Caenorhabditis elegans are appropriately regulated in hypoxia. To identify mediators of these...

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Identifiers

PMID: 25552276
DOI: 10.1534/genetics.114.173989
PMCID: PMC4349068

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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