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Article

Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARgamma.

Molecular cell - 12 Jan 2007

Ghisletti Serena, Huang Wendy, Ogawa Sumito, Pascual Gabriel, Lin Mu-En, Willson Timothy M, Rosenfeld Michael G, Glass Christopher K

Abstract excerpt

Transrepression is widely utilized to negatively regulate gene expression, but the mechanisms by which different nuclear receptors effect gene- and signal-specific transrepression programs remain poorly understood. Here, we report the identification of alternative SUMOylation-dependent mechanisms...

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Share to Histone Deacetylases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Cytoplasmic and Nuclear

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Source

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Identifiers

PMID: 17218271
DOI: 10.1016/j.molcel.2006.11.022
PMCID: PMC1850387

Genes

SUMO1
SUMO2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17218271-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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