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Article

Therapeutic angiogenesis by transplantation of induced pluripotent stem cell-derived Flk-1 positive cells

22 Sept 2010

Abstract excerpt

BACKGROUND: Induced pluripotent stem (iPS) cells are the novel stem cell population induced from somatic cells. It is anticipated that iPS will be used in the expanding field of regenerative medicine. Here, we investigated whether implantation of fetal liver kinase-1 positive (Flk-1+) cells derived from iPS cells could improve angiogenesis in a mouse hind limb model of ischemia. RESULTS: Flk-1+ cells were induced...

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PMID: 20860813
DOI: 10.1186/1471-2121-11-72

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