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Enhanced angiogenesis by mesenchymal stem cells based on Hyaluronic Acid hydrogel combined with GM-CSF and IL-2 in a rat model of hindlimb ischemia

2024-12-19

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<title>Abstract</title> <p>Background The clinical application of stem cells in restoring ischemic lower limb perfusion has been hindered by challenges. To promote the directed differentiation of mesenchymal stem cells(MSCs) into endothelial cells(ECs) and enhance the paracrine effect, this paper aim to find a combined therapy for angiogenesis. Methods MSCs based on Hyaluronic Acid(HA) hydrogel combined with GM...

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Literature Corpus work
1e60390f-5750-53dc-b5d6-5ea1ea1ba319
DOI
10.21203/rs.3.rs-5348024/v1
Open publication

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