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Efficient Engraftment of Human Induced Pluripotent Stem Cell-Derived Hepatocyte-Like Cells in uPA/SCID Mice by Overexpression of FNK, a Bcl-xL Mutant Gene.

Cell transplantation - 1 Jan 2015

Nagamoto Yasuhito, Takayama Kazuo, Tashiro Katsuhisa, Tateno Chise, Sakurai Fuminori, Tachibana Masashi, Kawabata Kenji, Ikeda Kazuo, Tanaka Yasuhito, Mizuguchi Hiroyuki

Abstract excerpt

Human liver chimeric mice are expected to be applied for drug toxicity tests and human hepatitis virus research. Human induced pluripotent stem cell-derived hepatocyte-like cells (iPSC-HLCs) are a highly attractive donor source for the generation of human liver chimeric mice because they can be produced on a large scale and established from an individual. Although these cells have been successfully used to...

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PMID: 24806294
DOI: 10.3727/096368914X681702

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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