Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells.

Blood - 1 Feb 2004

Haigh Jody J, Ema Masatsugu, Haigh Katharina, Gertsenstein Marina, Greer Peter, Rossant Janet, Nagy Andras, Wagner Erwin F

Abstract excerpt

Relatively little is known about the modulators of the vascular endothelial growth factor A (VEGF-A)/Flk1 signaling cascade. To functionally characterize this pathway, VEGF-A stimulation of endothelial cells was performed. VEGF-A-mediated Flk1 activation resulted in increased translocation of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Movement
Share to Endothelium, Vascular
Share to Enzyme Activation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Vitro Techniques

Share to Protein-Tyrosine Kinases

Share to Stem Cells

Share to Vascular Endothelial Growth Factor A

Share to Vascular Endothelial Growth Factor Receptor-2

Source

Identifiers

PMID: 14525765
DOI: 10.1182/blood-2003-07-2343

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-14525765-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Activated Fps/Fes partially rescues the in vivo developmental potential of Flk1-deficient vascular progenitor cells.PMID 14525765Read ↗

Isolation and propagation of yolk-sac-derived endothelial cells from a hypervascular transgenic mouse expressing a gain-of-function fps/fes proto-oncogene.Semantic proximity Read ↗

Hemostatic and hematological abnormalities in gain-of-function fps/fes transgenic mice are associated with the angiogenic phenotype.Semantic proximity Read ↗

Activated Fes protein tyrosine kinase induces terminal macrophage differentiation of myeloid progenitors (U937 cells) and activation of the transcription factor PU.1.Semantic proximity Read ↗

The VEGF receptor Flt-1 spatially modulates Flk-1 signaling and blood vessel branchingSemantic proximity Read ↗

MEIS1 Regulates Hemogenic Endothelial Generation, Megakaryopoiesis, and Thrombopoiesis in Human Pluripotent Stem Cells by Targeting TAL1 and FLI1Semantic proximity Read ↗

Induction of a hemogenic program in mouse fibroblasts.Semantic proximity Read ↗

An expandable, inducible hemangioblast state regulated by fibroblast growth factor.Semantic proximity Read ↗

Soluble Flt-1 regulates Flk-1 activation to control hematopoietic and endothelial development in an oxygen-responsive manner.Semantic proximity Read ↗

Mouse flt-1 promoter directs endothelial-specific expression in the embyroid body model of embryogenesis.Semantic proximity Read ↗

Basic fibroblast growth factor positively regulates hematopoietic development.Semantic proximity Read ↗

Fps/Fes and Fer protein-tyrosinekinases play redundant roles in regulating hematopoiesis.Semantic proximity Read ↗

Endothelial cells require functional FLVCR1a during developmental and adult angiogenesisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.