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Article

Vascular incorporation of endothelial colony-forming cells is essential for functional recovery of murine ischemic tissue following cell therapy.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2012

Schwarz Theresa M, Leicht Simon F, Radic Tamara, Rodriguez-Arabaolaza Iker, Hermann Patrick C, Berger Frank, Saif Jaimy, Böcker Wolfgang, Ellwart Joachim W, Aicher Alexandra, Heeschen Christopher

Abstract excerpt

OBJECTIVE: Cord blood-derived human endothelial colony-forming cells (ECFCs) bear a high proliferative capacity and potently enhance tissue neovascularization in vivo. Here, we investigated whether the leading mechanism for the functional improvement relates to their physical vascular incorporation or perivascular paracrine effects and whether the effects can be further enhanced by dual-cell-based therapy,...

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PMID: 22199368
DOI: 10.1161/ATVBAHA.111.239822

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MSC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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