Article

Interpreting Randomized Controlled Trials

2023-09-04

Abstract excerpt

This article describes rationales and limitations for making inferences based on data from randomized controlled trials (RCTs). We argue that obtaining a representative random sample from a patient population is impossible for a clinical trial because patients are accrued sequentially over time and thus comprise a convenience sample, subject only to protocol entry criteria. Consequently, the trial’s sample is unli...

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Literature Corpus work: 9353f5f8-59bf-5c68-ae5a-2f54f27e281d
DOI: 10.20944/preprints202309.0093.v1

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