Article

A Novel Feasibility Study Design Enabling Informative Clinical Trials in Low Resource Settings: the Pop-Up Prevalence study with Private Ethics (PUPPE)

2024-01-03

Abstract excerpt

The design of randomized controlled trials for low-resource settings has unique challenges. One challenge is ensuring recruitment success in the face of a lack of information about prevalence of disease in the population. What disease burden data may exist is old and from distant regions, adding guesswork into site design. This leads to a high chance that the sample size will not be recruited in any reasonable tim...

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Literature Corpus work: 68d34ee1-e734-5f1c-a8bf-99692b8b5cd8
DOI: 10.20944/preprints202401.0020.v1

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