Article
Evaluation of molecular markers of mesenchymal phenotype in melanoma.
Melanoma research - 1 Dec 2010
Mikesh Leann M, Kumar Manish, Erdag Gulsun, Hogan Kevin T, Molhoek Kerrington R, Mayo Marty W, Slingluff Craig L
Abstract excerpt
The epithelial to mesenchymal transition is a developmental process allowing epithelial cells to dedifferentiate into cells displaying mesenchymal phenotypes. The pathological role of epithelial to mesenchymal transition has been implicated in invasion and metastasis for numerous carcinomas, yet limited data exist addressing whether mesenchymal transition (MT) occurs in malignant melanoma cells. Our group...
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