Article
Biologic determinants of uveal melanoma metastatic phenotype: role of intermediate filaments as predictive markers.
Laboratory investigation; a journal of technical methods and pathology - 1 Feb 1998
Hendrix M J, Seftor E A, Seftor R E, Gardner L M, Boldt H C, Meyer M, Pe'er J, Folberg R
Abstract excerpt
The long-range goal of our research is to develop intervention strategies based on newly discovered biologic mechanisms responsible for the invasive dissemination of metastatic uveal melanoma. To accomplish this goal, we have focused on the biologic relevance of novel marker proteins contributing to the uveal melanoma metastatic phenotype. The expression of vimentin intermediate filaments (IFs), a mesenchymal...
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