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Article

Inherited genetic susceptibility to monoclonal B-cell lymphocytosis.

Blood - 23 Dec 2010

Crowther-Swanepoel Dalemari, Corre Tanguy, Lloyd Amy, Gaidano Gianluca, Olver Bianca, Bennett Fiona L, Doughty Chi, Toniolo Daniela, Caligaris-Cappio Federico, Calligaris-Cappio Federico, Ghia Paolo, Rossi Davide, Rawstron Andy C, Catovsky Daniel, Houlston Richard S

Abstract excerpt

Monoclonal B-cell lymphocytosis (MBL) is detectable in > 3% of the general population. Recent data are compatible, at least in a proportion of cases, with MBL being a progenitor lesion for chronic lymphocytic leukemia (CLL) and a surrogate for inherited predisposition. Common single nucleotide polymorphisms (SNPs) at 2q13 (rs17483466), 2q37.1 (rs13397985), 2q37.3 (rs757978), 6p25.3 (rs872071), 8q24.21...

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Identifiers

PMID: 20855867
DOI: 10.1182/blood-2010-07-294975

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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