Article
Inherited predisposition to CLL is detectable as subclinical monoclonal B-lymphocyte expansion.
Blood - 1 Oct 2002
Rawstron Andy C, Yuille Martin R, Fuller Julie, Cullen Matthew, Kennedy Ben, Richards Stephen J, Jack Andrew S, Matutes Estella, Catovsky Daniel, Hillmen Peter, Houlston Richard S
Abstract excerpt
Monoclonal chronic lymphocytic leukemia (CLL)-phenotype cells are detectable in 3.5% of otherwise healthy persons using flow cytometric analysis of CD5/CD20/CD79b expression on CD19-gated B cells. To determine whether detection of such CLL-phenotype cells is indicative of an inherited predisposit...
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