Article
Inherited susceptibility to CLL.
Advances in experimental medicine and biology - 1 Jan 2013
Speedy Helen E, Sava Georgina, Houlston Richard S
Abstract excerpt
Chronic lymphocytic leukaemia (CLL) is the most common lymphoid malignancy in Western countries, accounting for around a quarter of all leukaemias. Despite a strong familial basis to CLL, with risks in first-degree relatives of CLL cases being increased around sevenfold, the inherited genetic basis of CLL is currently largely unknown. The failure of genetic studies of CLL families to provide support for a major...
Topics
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Genotype
- Humans
- Leukemia, Lymphocytic, Chronic, B-Cell