Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Polyfunctional T cells in human tuberculosis

20 Jul 2010

Abstract excerpt

Studies of chronic viral infections have highlighted the phenotypic and functional heterogeneity of antigen-specific T cells and suggested that polyfunctional T cells that secrete multiple cytokines and are able to proliferate on encounter with antigen are more likely than single cytokine secretors to represent correlates of protective immunity. These findings have prompted the evaluation of such T-cell responses...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20853500
DOI: 10.1002/eji.201040731

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Polyfunctional T cells in human tuberculosisPMID 20853500Read ↗

Polyfunctional T-cells and effector memory phenotype are associated with active TB in HIV-infected patients.Semantic proximity Read ↗

Genome-Based In Silico Identification of New Mycobacterium tuberculosis Antigens Activating Polyfunctional CD8+ T Cells in Human TuberculosisSemantic proximity Read ↗

Polyfunctional Mycobacterium tuberculosis-specific effector memory CD4+ T cells at sites of pleural TB.Semantic proximity Read ↗

T-cell immunophenotyping distinguishes active from latent tuberculosis.Semantic proximity Read ↗

Analysis of Mycobacterium tuberculosis-specific CD8 T-cells in patients with active tuberculosis and in individuals with latent infection.Semantic proximity Read ↗

Double‐ and monofunctional CD4<sup>+</sup> and CD8<sup>+</sup> T‐cell responses to <i>Mycobacterium tuberculosis</i> DosR antigens and peptides in long‐term latently infected individualsSemantic proximity Read ↗

Human CD4 T-Cells With a Naive Phenotype Produce Multiple Cytokines During Mycobacterium Tuberculosis Infection and Correlate With Active Disease.Semantic proximity Read ↗

Characterization of <i>Mycobacterium tuberculosis</i>–Specific Cells Using MHC Class II Tetramers Reveals Phenotypic Differences Related to HIV Infection and Tuberculosis DiseaseSemantic proximity Read ↗

MAIT cells are minimally responsive to Mycobacterium tuberculosis within granulomas, but are functionally impaired by SIV in a macaque model of SIV and Mtb co-infectionSemantic proximity Read ↗

HIV-1 infection alters CD4+ memory T-cell phenotype at the site of disease in extrapulmonary tuberculosis.Semantic proximity Read ↗

Different phenotypes of CD8+ T cells associated with bacterial load in active tuberculosis.Semantic proximity Read ↗

Patients with Tuberculosis Have a Dysfunctional Circulating B-Cell Compartment, Which Normalizes following Successful Treatment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.