Article
Different phenotypes of CD8+ T cells associated with bacterial load in active tuberculosis.
Immunology letters - 1 Jul 2014
Silva Bruna Daniella de Souza, Trentini Monalisa Martins, da Costa Adeliane Castro, Kipnis Andre, Junqueira-Kipnis Ana Paula
Abstract excerpt
Tuberculosis is an infectious disease that affects millions of people worldwide with an annual mortality rate of 1.3 million. The mechanisms contributing to the loss of balance of immune responses and progression to active tuberculosis disease are unknown. Although CD4+ and CD8+ T cells and the cytokines they produce are crucial for protection against tuberculosis they have different roles in tuberculosis...
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