Article
T-cell immunophenotyping distinguishes active from latent tuberculosis.
The Journal of infectious diseases - 1 Sept 2013
Pollock Katrina M, Whitworth Hilary S, Montamat-Sicotte Damien J, Grass Lisa, Cooke Graham S, Kapembwa Moses S, Kon Onn M, Sampson Robert D, Taylor Graham P, Lalvani Ajit
Abstract excerpt
BACKGROUND: Changes in the phenotype and function of Mycobacterium tuberculosis (M. tuberculosis)-specific CD4+ and CD8+ T-cell subsets in response to stage of infection may allow discrimination between active tuberculosis and latent tuberculosis infection. METHODS: A prospective comparison of M. tuberculosis-specific cellular immunity in subjects with active tuberculosis and latent tuberculosis infection, with...
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