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Correlation of APOE polymorphism, expression, and plasma levels with cardiac comorbidities among lipodystrophy in HIV-infected patients.

Clinica chimica acta; international journal of clinical chemistry - 15 Jan 2025

Shyamveer, Antony Jenitha A, Bhattacharya Meenakshi, Mahajan Supriya D, Ali Nemat, Rashid Khan Mohammad, Singh HariOm

Abstract excerpt

Lipodystrophy in HIV-infected patients (LDHIV) includes morphological and metabolic abnormalities, including lipid and glucose metabolism. ApoE plays a role in the transport and clearance of lipoprotein. In the general population, ApoE 112 (rs429358) and 158 (rs7412) polymorphisms were linked to severe dyslipidemia. Therefore, we investigated ApoE polymorphism using PCR-RFLP in 200 HIV patients (100 with...

Topics

Humans
Apolipoproteins E
Male
Female
HIV Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Adult

Middle Aged

Polymorphism, Genetic

Case-Control Studies

HIV-Associated Lipodystrophy Syndrome

Comorbidity

Lipodystrophy

Genotype

Source

Identifiers

PMID: 39313065
DOI: 10.1016/j.cca.2024.119969

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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