Article
An association analysis of Per2 with panic disorder in the Japanese population.
Journal of human genetics - 1 Oct 2011
Otowa Takeshi, Tochigi Mamoru, Kawamura Yoshiya, Sugaya Nagisa, Yoshida Eiji, Inoue Ken, Yasuda Shin, Umekage Tadashi, Ebisawa Takashi, Tanii Hisashi, Kaiya Hisanobu, Okazaki Yuji, Kato Nobumasa, Sasaki Tsukasa
Abstract excerpt
Panic disorder (PD) is a severe and chronic psychiatric disorder, with genetic components underlying in its etiology. The PERIOD2 (Per2) gene has been reported to be associated with familial advanced sleep phase syndrome. Considering the high frequency of sleep disturbance in PD, Per2 may be a candidate gene for PD. Therefore, we conducted a two-stage case-control association study in the Japanese population. In...
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