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Article

Protein-DNA Interaction at the Origin of Neurological Diseases: A Hypothesis

1 Oct 2010

Abstract excerpt

A number of neurodegenerative diseases, including Alzheimer's disease, tauopathies, Parkinson's disease, and synucleinopathies, polyglutamine diseases, including Huntington's disease, amyotrophic lateral sclerosis, and transmissible spongiform encephalopathy, are characterized by the existence of a protein or peptide prone to aggregation specific to the disease: amyloid-β, tau protein, α-synuclein, atrophin 1,...

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PMID: 20847445
DOI: 10.3233/jad-2010-100189

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